Past Issue

Past Issue

Multi-omics data integration for precision medicine in cervical cancer a comprehensive computational approach

Cervical cancer remains a major and widespread global health problem and continues to be a global health problem despite significant progress. One of the biggest challenges facing the healthcare system is advances in diagnosis and treatment. In this  study, we combined multiple types of biological data, specifically genomic, transcriptomic and proteomic data, to find usable cancer targets and treatments that are not only prevalent but also have the potential to impact cancer progression.

Formulation, characterization and evaluation of topical gel containing miconazole nitrate for fungal infection

Miconazole is an imidazole derivative and used for the treatment of local and synthetic fungal infection. The oral use of miconazole is not recommended as it has many side effects. The miconazole topical gel formulation is made for better patient compliance and to reduce the dose of drug and to avoid side effects like liver damage and kidney damage. Gel was formulated by using different polymers.

A Comprehensive Review on the Preparation and Development of Probiotic Mixed Fruit Jelly Candy

In recent years, probiotics—live microorganisms that confer health benefits when consumed in sufficient amounts—have become pivotal in promoting gut health. Their benefits, including enhanced digestion, alleviation of lactose intolerance, and disease prevention, have long been recognized, with early contributions from Tissier’s research on bifidobacteria in breastfed infants. The combination of probiotics with prebiotics has garnered increasing attention for its potential to further support gut microbiota.

Pharmacological and phytochemical evaluation of poornayu swarna prashan bindu

Poornayu Swarna Prashan Bindu is a combination of gold, go-ghrita and multi-herb which contains nine important herbs in fresh and dried form. The present study provides updated information on its phytochemical analysis, pharmacological properties, microbial limit, heavy metal study and probable mode of action of Poornayu Swarna Prashan Bindu. Organoleptical, Physio-chemical properties, microbial test, heavy metal study and probable mode of action of drug were evaluated as a primitive step to analyse the Poornayu Swarna Prashan Bindu.

A comprehensive review of dharniya mansik vega and its role in manisfestation of diseases

Ayurveda always emphasize the importance of health as a whole in terms of both Shareerika and Manasika Swasthya. Acharya Sushrut clearly defines health as balanced state of Dosa, Agni, Dhatu, Mala and Prasannata of Indriya and Manas. In the present era, there are many causes for the impairment in Manasika Swasthya. Among that not controlling the occurrence of Dharaniya Vega has a key role. Manasika Vega refers to the intensification of Dharaniya Vega, which includes emotions such as Kama (desire), Krodha (anger), Lobha (greed), Mada (pride), Matsarya (envy) and others.

Epidemiological profile of measles in the san health district from january 2021 to december 2023

Introduction: The fight against diseases, especially those preventable by vaccination, is a priority for the world’s health authorities. Measles remains one of the main causes of infant and child mortality despite the availability of a safe and effective vaccine. Prior to the introduction of mass vaccination in 1980, measles caused nearly 2.6 million deaths per year.Method: Our study was cross-sectional, descriptive and analytical. It took place from 01 to 31 January 2024 in the San health district.

Association of hormonal fingerprints with malocclusion among 18-25 years old dental students – a cross-sectional study

Aim & Objective: The study aims to assess the association of hormonal fingerprints with malocclusion among 18-25 years old dental students. Introduction: A ‘Hormonal Fingerprint’ biomarker is the ratio of the lengths of the second and fourth digits. In dentistry, few research have been conducted to assess the impact of hormonal fingerprints on oral health, prompting us to develop a new approach for predicting malocclusion. Material & Methods: A total of 160 dental students were randomly selected from both gender of age group 18-25 years.

Chronic Suppurative Otitis Media Infections: Bacterial Profile and Demographic Features Among Patients Attending Tertiary Care Hospital

Introduction: Chronic suppurative otitis media (CSOM) can cause intracranial and extracranial complications. Reducing its prevalence may have both immediate and long-term health advantages. Understanding the local microbial flora in CSOM is critical before beginning empirical therapy. Our study sought to evaluate the link between bacterial profiles and demographic features in patients admitted to tertiary care institutions with persistent suppurative otitis media infections.