Past Issue

Past Issue

Development and Validation of RP-HPLC Method for the determination of Linezolid in pharmaceutical dosage form

A simple, precise, accurate sensitive and specific RP-HPLC method for the determination of Linezolid in pharmaceutical dosage form. Chromatogram was run through Sunfire C18 150 x 4.6 mm, 5m. Mobile phase containing 0.01N Potassium dihydrogen phosphate: Methanol taken in the ratio 65:35 was pumped through column at a flow rate of 1.2ml/min. Buffer used in this method was 0.01N Potassium dihydrogen phosphate (4.8ph) buffer. Temperature was maintained at 30°C. Optimized wavelength selected was 252.0nm. Retention time of Linezolid  was  found  to  be  2.469  min.

From Bench to Clinic: A Review of Evolving Landscape of Regenerative Dentistry

Regenerative dentistry is an emerging and interdisciplinary field that seeks to restore the structure and function of damaged dental tissues using principles derived from stem cell biology, tissue engineering, and molecular science. This review paper offers an in-depth overview of the development, ideas, and prospects of regenerative dentistry treatments. By integrating biologically driven approaches with clinical practice, regenerative dentistry offers promising alternatives to conventional dental treatments such as root canals, implants, and prosthetics.

Exploration of social media handles to enhance communication in the construction industry

The use of information technology (IT) in this twenty first century is rapidly gaining root in many industries including construction due to its numerous benefits. In the area of promoting communication, social media handles may be viewed as propelling factor and that this study zoomed into the proposition to establish whether social media handles could be explored as effective way to enhance communication in the construction industry.

Restoring Union in Humeral Shaft Non union using Fibular grafts and Locking plates : A Prospective study

Introduction: Humeral non-union, which can occur in conservatively treated fractures and surgically managed cases, presents significant challenges. Combining non- vascularized fibular autografts (NVFG) with locking compression plates (LCP) may offer a reliable method for achieving bone union and restoring function in such patients. Therefore, this study aims to evaluate the functional outcomes of autologous NVFG and LCP for failed fixation of humeral shaft with atrophic gap non-union.

Exploring the Relationship Between Self-Esteem and Self-Harm: A Gender-Based Analysis

This study investigates the relationship between self-esteem and self-harm behaviours among Indian Population aged 13–50. Using the Rosenberg Self-Esteem Scale (RSE) and the Self-Harm Inventory (SHI), data were collected from 78 participants. Results showed a significant negative correlation between self-esteem and self-harm (r = −0.611, p < 0.0001), with a stronger association observed among females (r = −0.644) than males (r = −0.476).

Fish Diversity of Bor Beel and Kanakukura Beel of Barpeta District, Assam – A Comparative Study

The present study on fish diversity on two different water bodies of Barpeta district of lower Assam, i.e -Borbeel and Kanakukurabeel was done from March, 2024 to Maerch, 2025. A total of 43 fish species which comprise28 genera, 15 families and 5 orders were recorded while36 fish species belong to the Borbeel and 37 fish species were from Kanakukurabeel.Cyprinidae family is the most dominant, which includes 15 species in both Borbeel and Kanakukurabeel.

A Novel Rp-Hplc Method Development and Its Validation For Assay Of Chlorpheniramine Maleate Injection

Chlorpheniramine Maleate injection (CPM) is a first-generation H1 antihistamine widely utilized for the management of allergic disorders. Thevarious pharmacopoeias currently employ UV spectroscopy method to determine the interference of preservative with API. This method lacks in sensitivity, specificity and robustness, particularly in the formulations as they contain various preservatives such as Chlorbutol, phenol, phenyl mercuric nitrate and benzyl alcohol, which interferes with the analysis.

Assessing the Role of Low-Level Laser Therapy in Reducing Pain during Initial Orthodontic Tooth Movement

Background: Pain during orthodontic treatment, particularly during the levelling and alignment phase, is a major concern that can impact patient compliance and treatment experience. While several methods exist to manage this discomfort, many have limitations including potential interference with tooth movement. Low-Level Laser Therapy (LLLT) has emerged as a promising non-pharmacological approach to reduce orthodontic pain.

Role of Fungi in Oral Infections – A Comprehensive Literature Review for Dental Professionals

For thousands of years, oral fungal infections have existed in human history.Hippocrates, who lived between 460 and 370 BCE, was the first person to report occurrences of oral aphthae that could have been oral candidiasis. While infections like cryptococcosis, aspergillosis, and mucormycosis are relatively rare in the mouth, oral candidiasis became widely recognized during the AIDS epidemic. It was a major opportunistic infection, signaling the progression from HIV to AIDS. This highlighted the vital role of our immune system in preventing fungal infections.

A case report on astroblastoma

Background: Astroblastoma is a rare neuroepithelial tumor that often originates in the cerebral hemisphere of children and young adults. Diagnosis of this obscure neoplasm can be difficult because these tumors are so infrequently encountered and share common radiological and neuropathological features of other glial neoplasms.  Case Description: We present a case of a low-grade astroblastoma diagnosed in a 30-year-old female with complaints of headache, vomiting and vision changes. CT was done which revealed anintra-axial neoplasm in the left frontal lobe.