Telangiectatic osteosarcoma is one of the rare subtypes of osteosarcoma and accounts for 4% of all osteosarcomas. Telangiectatic osteosarcoma is a rare variant of osteosarcoma with distinctive radiographic, gross, and microscopic features and prognostic implications. The common sites for the tumor location are the fastest growing long tubular bones; the femur is involved most frequently, followed in frequency by the tibia and humerus – a distribution similar to that of conventional osteosarcoma. This primary high-grade osteosarcoma of the bone is commonly seen in children, adolescents, and young adults. By contrast, primary osteosarcoma in atypical locations such as the axial skeleton or soft tissues occurs in middle to late adulthood. The location, prognosis, and treatment of this unusual lesion mirror that of conventional osteosarcoma.
