Past Issue

Past Issue

Synergistic Potential of Curcumin and Berberine: From Plant-Origin Compounds to Nanoparticle-Enabled Therapeutics

Curcumin, a polyphenolic diarylheptanoid derived from Curcuma longa (turmeric), and berberine, an isoquinoline alkaloid prevalent in Berberis aristata (Indian barberry), are two powerful bioactive chemicals of plant origin, exhibiting significant antibacterial, anti-inflammatory, and anticancer activities. This review examines the botanical origins, chemical characteristics, principle pharmacological qualities, and significant limitations—specifically inadequate aqueous solubility and limited oral bioavailability that hinder clinical applications.

abrication and thermal properties of PVC

Poly(vinyl chloride) (PVC) films doped with different concentrations of FeSO4 were prepared by solution casting technique and their  thermal, structural, morphological, optical and magnetic properties were investigated. Thermal properties of these films were investigated employing differential scanning calorimetry (DSC) and thermo gravimetric analysis (TGA). Using the DSC thermograms, glass transition temperature (Tg) and melting temperature (Tm) of the films were measured.

Synthesis of tetraazolo[1,5-a]quinolin analogues containing pyrimidine and thiazolidinone as antimicrobial agents

A series of new 2-(aryl)-3-(4-phenyl-6-[1,2,3,4]tetraazolo[1,5-a]quinolin-4-yl-2-pyrimidinyl)-1,3-thiazolan-4-one 15(a-j)has been synthesized by incorporating tetrazole, pyrimidine and thiazolidinone rings in one molecule for intensifying biological activity. Further, all the newly synthesized compounds have been assayed for their antimicrobial activity against Gram-positive bacteria viz.  Bacillus subtilis, Bacillus sphaericus and Staphylococcus aureus, and Gram-negative bacteria viz.

A checklist of ichthyofaunal resources of the Palla River of Assam, India

Freshwater ecosystems throughout the world play very crucial role in ichthyofaunal diversity as well as fishery potential.North-east India is considered a hotspot of ichthyofaunal resources. The Palla river flows through the Baksa and Barpeta districts of Assam. It is a tributary of the Chaulkhowa river, which merges with the Brahmaputra River. In the present study, a total of 56 species of fish have been identified under 43 genera, 8 orders and 19 families from the four sampling sites of the Palla river, Assam, India (Table 1).

Cleft Laterality- A Review

Laterality in unilateral facial cleftshas been shown to follow non-random patterns and to influence morphology, surgical complexity, functional outcomes, and psychosocial adjustment. This review surveys existing literature to describe the existing knowledge about laterality- epidemiology, developmental and genetic underpinnings, morphological and functional consequences, implications for surgery and long-term outcomes. We conclude that though the leftsided unilateral clefts are more frequent, the side of cleft has meaningful, though often subtle, impact on outcomes.

Effectiveness of structured educational programme on knowledge regarding prevention of hypertensive complications among hypertensive patients residing inselected area at sikar

Abstract: A study knowledge regarding prevention of hypertensive complications among hypertensive patients residing in selected area at Sikar. Material & Method: The quantitative research approach and pre- experimental one group pre test post test design was adopted for this study. Non probability convenience sampling technique was used for sample selection. The data were observed from 300hypertensive patients. The study was conducted at Radhakrishnan Pura, Kishan Colony, Veer Teja Colony, Jaldhari Nagar, Sikar. Structured question tool was used to gather the data.

Improving the seismic resistance of cultural heritage sites- Old Bazaar of Gjirokastra, Albania

Masonry, as one of the oldest construction techniques, has been used in historical sites. Assessment of structural performance under seismic effects is a very important step for restoration process of historic buildings that represent construction techniques and material characteristics of their era. Following a methodology that includes research, diagnostics, safety analysis and the determination of effective reinforcement intervention techniques must be done in respect of the historical values ​​and the original conception of the building.

Studies on effects of Heavy metals in channa gachua (Hamilton, 1822) from Tunia River, Bongaigaon District, Assam, India

The heavy metals like Ph, Hg, Cd, Cr, Cu, Zn, Mn, Ni, Ag, etc. of which As, Cd, Pb and Hg are considered biotoxin chemicals to humans, animals, fishes and environment Excessive concentrations of these heavy metals has been a matter of serious concern as they destabilize ecosystems because of their bioaccumulation in organisms, and toxic effects on biota and causing death in most living beings including wildlife.

Long-term exposure toemamectin benzoate induces alterations in transaminase activity in zebrafish (danio rerio)

Emamectin benzoate (EMB), a macrocyclic lactone insecticide, is extensively used to control insect pests in agriculture and management of parasites in aquaculture farms. Owing to its widespread application, EMB has been detected in soil and water samples throughout the world and raised environmental pollution concerns. Due to itshigh efficiency, persistence, residue and bioaccumulation properties, EMB has caused adverse effects on aquatic organisms. Thus, in the current study, the toxicity of EMB on marker enzymes of zebrafish (Danio rerio) was assessed.

Applications of IoT in Power System Analysis

The rapid evolution of the Internet of Things (IoT) has transformed modern power systems by enabling real-time monitoring, automation, predictive analytics, and improved decision-making. The integration of IoT with smart sensors, cloud platforms, communication networks, and advanced data analytics supports more efficient power system analysis. This study explores the key applications of IoT in power system analysis, including load forecasting, fault detection, condition monitoring, grid stability assessment, and asset management.