Introduction: Type 2 Diabetes mellitus is associated with higher risk of cognitive dysfunction, dementia, and depression in the elderly. Type 2 diabetes has been associated with decrease in verbal memory, working memory, immediate recall, verbal fluency and attention. Mild cognitive impairment is believed to be a high-risk condition for the development of clinically probable Alzheimer disease. These patients also have an increased need for personal care and increased rates of hospitalization. Screening and detecting the elderly diabetics at this stage is of utmost importance for prevention of Alzheimer disease. Materials and Methods: The cross sectional study was conducted at RL JALAPPA hospital, Kolar for a period of 3 months. 52 elderly type 2 diabetes mellitus who met the inclusion and exclusion criteria were included, and MMSE was done and patients with mild cognitive impairment were given WHOQOL-BREF questionnaire. Quality of life (QOL) was assessed based on 4 domainsPhysical health, Psychological, Social relationships, Environment domain. Observation: Fifty two elderly type 2 diabetes patients with mild cognitive impairment were included in the study, with mean age 65.79 ±4.53 years. 48% of them had duration of diabetes of less than 5 years. Most of them were treated with oral hypoglycemic drugs. They had a FBS of 179.69 ± 80.71 and PPBS 250.78 ± 98.13. 52.3% patients had a coexisting hypertension. Mean MMSE Score in subjects was 20.94 ± 2.04.The most affected domain was the psychological and social relationship domain with mean score of 50.73 and 46.48 respectively. Negative correlation was observed for QOL domains with respect to MMSE scores. This indicated that there is a decrease in QOL with respect to mild qualitative impairment. Conclusion: QOL was decreased among diabetic patients with mild cognitive impairment. Good family support, screening programs and active intervention for patients with mild cognitive impairment tend to improve the QOL and reduce the further worsening of QOL
