In order to study the effect of drought stress on sesame (Sesamum indicum L.) genotypes, a split plot experiment was carried out based on a Randomized Completely Block Design with two replications. The irrigation regimes compromised of Full irrigation (I1), Moderate drought stress (I2) and severe drought stress (I3). The subplots were allocated to ten different genotypes of sesame. In this experiment different characteristics including plant height, number of the primary branches, number of capsules, 1000- seed weight, number of seeds per capsule, seed yield, biological yield and harvest index were measured. Analysis of variance showed that there was significant difference between genotypes for all of the studied traits, except for harvest index (%). Irrigation intervals had significant effects on number of primary branches per plant, seeds per capsule, 1000-seed weight, biological yield and seed yield. Interaction effect of irrigation ×genotype was significant for plant height, number of capsules per plant, seed yield and biological yield. Different tolerance indices including MP, TOL, SSI, STI and HM were calculated the highest value for seed yield was observed in in Darab14 (2079.1) (Kg/m2). So, this superior genotype could be proposed for cultivation in arid regions
