STUDY ON EFFECT OF NSAID’S IN ACUTE MPDS AND NSAID’S AND SSRI’S IN CHRONIC MPDS

Research Article
V. Akhila and Kuldeep Moras
DOI: 
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Subject: 
Medicine
KeyWords: 
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Abstract: 

Aim : To see the effect of NSAIDs’ in acute MPDS and NSAIDs’ with SSRI in chronic MPDS using the universal tool for pain assessment before and after treatment and to assess the age and sex prevalence of the disorder.
Materials And Methods: In this study 30 patients with acute MPDS and 30 patients with chronic MPDS of either gender who were diagnosed using the research diagnostic criteria for MPDS were selected. The patients were of the age group 18 to 60 years. Patients with acute MPDS were given NSAIDs’ for one week and those with chronic MPDS were given NSAIDs’
and SSRI for one month. Pain was assessed before and after treatment using universal tool for pain assessment.
Statistical Analysis: It is a prospective study where the severity of symptoms in patients was assessed before and after treatment, the age, sex prevalence of the disorder was calculated using mean, frequency standard deviation and paired t test.
Result: A total of 60 patients - 30 with acute MPDS and 30 with chronic MPDS were subjected to NSAIDS alone and NSAIDS and SSRI in combination respectively. The study showed female preponderance. The mean score with universal pain assessment tool before and after treatment was 8 and 3.5 for acute MPDS and 7 and 3 for chronic MPDS respectively. The student t test showed p-value of <0.005 which was significant.
Conclusion: Treatment with NSAIDS for acute MPDS for one week and NSAIDS and SSRI for chronic MPDS for one month decreased the intensity and severity of symptoms in MPDS. However the long term effects on quality of life could not be assessed. The study needs to be conducted in a large scale to evaluate the consistency and accuracy of the test.