The liquidsolid technique is a novel and advantageous method for modifying the dissolution rate of drugs that are insoluble in water. Due to insufficient dissolution rate of the drug, which is a controlling factor in oral bioavailability and one of the most exciting aspects of drug development, oral administration of poorly water soluble compounds frequently necessitates high doses in order to achieve therapeutic plasma concentrations. The vast majority of newly developed drug candidates are lipophilic and insoluble in water. Improving the dissolution and bioavailability of these drugs is a major task for the pharmaceutical industry. This article's goal is to provide an overview of the liquisolid technique and to summarise its progress in pharmaceutics applications. The primary benefits of this approach are its low cost, ease of processing, and high potential in industrial production.
