Preliminary Hepatoprotective Activity Of Medicinal Plant Extracts Against Carbon Tetrachloride Induced Hepatotoxicity In Albino Rats

Research Article
G. Venkat Raji Reddy., R.Vijay Kumar., V. Rama., M. Krishna Reddy. and Y. Narsimha Reddy
Total cholesterol, HDL, LDL, Triglycerides, liver glycogen and liver protein.

Liver is one of the largest organs in human body and the chief site for intense metabolism and excretion. So it has a surprising role in the maintenance, performance and regulating homeostasis of the body. It is involved with almost all the biochemical pathways to growth, fight. But it is continuously and variedly exposed to environmental toxins and abused by poor drug habits and alcohol and prescribed and over-the- counter drug which can eventually lead to various liver ailments like hepatitis, cirrhosis and alcoholic liver disease. Modern medicines have little to offer for alleviation of hepatic diseases and it is chiefly the plant based preparations which are employed for their treatment of liver disorders. But there is not much drug available for the treatment of liver disorders. Therefore, many folk remedies from plant origin are tested for its potential hepatoprotective liver damage in experimental animal model. Carbon tetrachloride (CCl4 ) induced hepatotoxicity model is widely used for the study of hepatoprotective effects of drugs and plant extracts.