The role of Traditional Ethnobotanical Knowledge (TEK) for primary healthcare was carried out in the community of Loharbond region of Innerline Reserve forest, North-Eastern India. Using an intensive field participant observation methodology, we listed about 61 taxa of medicinal plants belonging to 43 families. Although Lamiaceae and Cucurbitaceae were mostly used but a large number of families contributed through single and double plants in each. Mikania micrantha, Azadirachta indica, Centella asiatica etc. had highest fidelity level (100%) and Dillenia indica (65%) had lowest fidelity level among most common species. Leaves (44%) were the most preferred plant parts and gastro-intestinal disorders was the commonest disease that was treated using TEK. There was huge agreement among ethno-medico-botanical informants by Factor of Informants Consensus (Fic) value ranging from 0.58 to 0.88, with an average value of 0.80. The knowledge on medicinal plants used by the people of Loharbond region seems to be well known to its culture and tradition.