Effect Of Chronic Exposure Of Monosodium Glutamate (Msg) Onviability And Rate Of Feeding In Two Different Strains Of Drosophila Melanogaster

Research Article
Deepak D and M S Krishna
LD50, Monosodium Glutamate (MSG), Excitotoxin, Drosophila melanogaster.

Monosodium Glutamate (MSG) is most widely used as a flavor enhancer. It has been used as food additive for over 100 years; however, its safety is a much debated issue. In this study, we assess the developmental toxicity of MSG on two strains, Oregon K and Oregon R of Drosophila melanogaster to determine the Median Lethal Dose (LD50). LD50 was found to be 10.03% for Oregon K and 12.83% for Oregon R. Significant difference in LD50 was observed between the strains. Further, significant variation in the larval rate of feeding was noticed in different concentrations of MSG.