Determination Of Estrogenicity Of Asoca Plant (Saraca Asoca Linn.) In Adult Female Ovariectomised Mice

Research Article
Anindita Deka, Jogen Chandra Kalita, Yungkham Rajeevkumar Singh and Manalisha Deka
DOI: 
xxx-xxxxx-xxxx
Subject: 
science
KeyWords: 
Phytoestrogen, Saraca asoka, ovariectomy, estrus
Abstract: 

The following study was carried to determine the phytoestrogenic property of Asoka plant, Saraca asoca, one of the foremost plants utilized from antiquity till date against different gynaecological ailments like uterine fibroids, relief of menstrual pain, treatment of menorrhagic etc. Oral administration of methanolic extract of bark of Saraca asoca was done in the ovariectomised mice at the dose of 500mg/kg body weight which showed marked induction of estrus, significant increase in uterine wet weight(p<0.0025) and also marked change in uterine size. Hence, it may be inferred that the extract may contain phytoestrogenic compounds that led to the following changes in the uterus of ovariectomised mice. Thus, Saraca asoca can be used as a potent remedy for curing estrogen deficient diseases.