Clinical Profile Of P. Vivax Malaria Related To Its Complication At Tertiary Care Centre

Research Article
Niyati Gosai and Nehal Shah
DOI: 
xxx-xxxxx-xxxx
Subject: 
science
KeyWords: 
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Abstract: 

Background: Plasmodium Vivax is the most widely distributed malarial parasite with an increase risk in human. Severe malaria due to P.vivax infection is increasingly observed now a day. With the implementation of molecular diagnosis, it has become evident that P.vivax as monoinfection could also cause multiple organ failure with life threatening complications.

Material and Method: We recruited 100 patients with confirmed P.vivax malaria during the study period from August 2013 to August 2014. After explaining the procedure in detail and with written consent from all patients, history and examination findings were noted in all patients .All patients were subjected to routine investigations. We followed up all patients till discharged or expired.

Result: We had 100 patients with plasmodium Vivaxmalaria infections either by smear or BY CARD test positive, Out of 100 patients 65 were male and 35 were female. Thrombocytopenia was the most common complication around 93% in present study. Other complications were anemia (47%), acute kidney injury (16%), hepatic dysfunction (24%), hypotension (21%), ARDS (5%) and cerebral malaria (10%). Mortality observed in P.vivax malaria was 7%.

Conclusion: Severe Vivax malaria is now very common with increasing morbidity and mortality. Thrombocytopenia is very common in severe Vivax malaria. Renal, hepatic, lungand cerebral involvement is also increasing now a day. Timely given appropriate treatment with Chloroquine or Artesunate based combination therapy with other supportive treatment can reduce multi organ dysfunction and mortality.